Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Hydroxychloroquine stomach pain Plaquenil sulfa Plaquenil drug insert Pregnancy hydroxychloroquine Do not use Plaquenil without telling your doctor if you are breast-feeding. Our blog on Lupus and Pregnancy has much more valuable information on this topic. Back to top. We hope that this blog has been helpful in answering some of your questions about Plaquenil and other antimalarial drugs used to treat lupus. Hydroxychloroquine is commonly used alongside other disease-modifying drugs including methotrexate – especially for rheumatoid arthritis. However, some drugs can interact with hydroxychloroquine. Indigestion remedies for example, antacids including some over-the-counter preparations can stop hydroxychloroquine being absorbed. Side effects of methotrexate include liver damage, lung damage, and a decreased ability to fight off infections. Eye damage can be a side effect of hydroxychloroquine. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Does methotrexate work without plaquenil Methotrexate and plaquenil - @Kristinsaba1988 - Scleroderma - 20151009., Hydroxychloroquine Side-effects, uses, time to work Chloroquin malaria Compare Methotrexate vs Plaquenil head-to-head with other drugs for uses, ratings, cost, side effects, interactions and more. Methotrexate rated 6.7/10 vs Plaquenil rated 6.8/10 in overall patient satisfaction. Methotrexate vs Plaquenil Comparison -. Rheumatoid Arthritis Drug Treatments Pros and Cons Everyday Health. Ask the Expert Plaquenil and Sjögren’s. Re Plaquenil - Can It Work Quickly? I tried to get on Plaquenil years ago, and couldn't tolerate it, but now I'm thinking there might be a lessor dose I should try. I'm new to the area, so don't have a rheumy yet. This study is created by eHealthMe based on reports of 23,242 people who take Methotrexate and Plaquenil from Food and Drug Administration FDA, and is updated regularly. On eHealthMe, you can evaluate side effects and drug interactions from 15 million FDA reports. Methotrexate for Your RA. Methotrexate is one of the most effective medications to treat rheumatoid arthritis RA. It's the first drug most doctors prescribe after you’re diagnosed. It will.