Please review the following URL and make sure that it is spelled correctly. Hi, I saw a rheumy for the first time last week, and he prescribed plaquenil, 200 mg twice a day. Chloroquine glioblastoma Chloroquine prostate cancer Plaquenil, hydroxychloroquine HCQ, is an anti-malarial medication that has been proven to be useful in the treatment of patients with rheumatoid arthritis RA, systemic lupus erythematosus SLE and other inflammatory and autoimmune diseases. The usual starting dose of Plaquenil is 200 mg twice a day or 400 mg once a day, administered orally, in people weighing 80 kg or more. The usual dosage works for most people who take Plaquenil, but it is possible to increase or decrease the dose based on individual needs. It's important to watch for possible side effects and toxicity. Do not take 2 doses at the same time or extra doses. While taking hydroxychloroquine, your skin may become more sensitive to the sun. It is important to wear sunscreen and protective clothing. He warned that it could take 2-6 months, though, which is what I've read here too. I started with just one pill a day for a week, and now am to take 2 pills per day. Didn't diagnose with Lupus yet, but said I definitely have something autoimmune going on and the plaq will help with the fatigue. I take 2 hydroxychloroquine Hydroxychloroquine or Plaquenil Medication Information., Taking Plaquenil for Rheumatoid Arthritis Does plaquenil cause fatiguePlaquenil back injuryWhat is plaquenil taken for Suppressive therapy should begin 2 weeks prior to exposure; however, failing this, an initial dose of 800 mg 620 mg base may be taken in 2 divided doses 6 hours apart.-Suppressive therapy should continue for 8 weeks after leaving the endemic area.-Each dose should be taken with a meal or a glass of milk. Use Malaria prophylaxis Hydroxychloroquine Dosage Guide with Precautions -. Hydroxychloroquine or Plaquenil Medication Information dosing, side.. Hydroxychloroquine Reviews Everyday Health. Like all DMARDs, they take time to work. Most patients start to feel their positive effects at 6-8 weeks, with maximum benefit at 3-6 months. Side effects can occur earlier. Is there anything I can do to reduce these side effects? Stomach Upset – for those taking two tablets, try splitting the dose. Also try taking it with or without food. Hydroxychloroquine comes as a tablet to take by mouth. For prevention of malaria in adults, two tablets are usually taken once a week on exactly the same day of each week. The first dose is taken 1 to 2 weeks before traveling to an area where malaria is common, and then doses are continued for 8 weeks after exposure. Nov 20, 2013 I take both minocycline and plaquenil. I tried weening myself off the plaquenil, but, couldn't take the pain. I've only been on the mino since February. But, so far I've had more good days than bad. And, that's a great thing. This time last year I believed my active days were over. I wasn't able to get out of bed for more than an hour at a time.