Janet Olson, DACVIM (Cardiology) of Veterinary Cardiology Specialists in Minneapolis, MN for this great VETgirl guest blog! Here, she discusses the appropriate and inappropriate uses of furosemide, the diuretic (commonly called Lasix in North America). Furosemide is the most common medication used in dogs with confirmed heart failure. Here are some general “DOs and DONʼTs” for Furosemide use. DOs 1) Prior to prescribing furosemide, a renal panel with electrolytes and a urine specific gravity should always be performed. This is necessary to establish a baseline for which to assess renal function and tolerance and response to therapy. 2) Any time the furosemide dose is increased, a renal panel with electrolytes should be performed. This is indicated to ensure continued tolerance to the medication. Used for prompt relief of edema in horses, cattle, dogs and cats associated with cardiac insufficiency and acute noninflammatory tissue edema. Dosage: Administer intramuscularly or intravenously. Cattle- 10 ml (500 mg) once daily or 5 ml (250 mg) twice daily at 12 hour intervals. Horses- 5-10 ml (250-500 mg) once or twice daily at 6 to 8 hour intervals. Dogs and cats- 1/4 to 1/2 ml per 10 lbs body weight given once or twice daily, permitting a 6 to 8 hour interval between treatments. Milk taken from animals during treatment for 48 hours after last treatment may not be used for food. Cattle may not be slaughtered for food within 48 hours following last treatment. Chemical name: 4-chloro-N-furfuryl-5-sulfamoylanthranilic acid. INDICATIONS Dogs, Cats & Horses: Furosemide Injection 5% is an effective diuretic possessing a wide therapeutic range. Cheap viagra brand Need to buy lisinopril Inderal drug Best online pharmacy to buy viagra Although furosemide is more rapidly absorbed from the oral solution 50. advisable for adults, an infusion rate not exceeding 4 mg LASIX per minute has been. When performing a furosemide trial, a dose of 2 mg/kg of furosemide PO BID is recommended. If you use too low of a dose and they donʼt respond, you. Furosemide is available in 12.5 mg, 20 mg, 40 mg, 50 mg and 80 mg tablets. The dose of furosemide recommended for dogs and cats is 1-2mg/pound once or. Absorption: 60–67% absorbed after oral administration (↓ in acute HF and in renal failure); also absorbed from IM sites. Metabolism and Excretion: Minimally metabolized by liver, some nonhepatic metabolism, some renal excretion as unchanged drug. TIME/ACTION PROFILE (diuretic effect)CNS: blurred vision, dizziness, headache, vertigo EENT: hearing loss, tinnitus CV: hypotension GI: anorexia, constipation, diarrhea, dry mouth, dyspepsia, ↑ liver enzymes, nausea, pancreatitis, vomiting GU: ↑ BUN, excessive urination, nephrocalcinosis Derm: Edema PO: (Adults) 20–80 mg/day as a single dose initially, may repeat in 6–8 hr; may ↑ dose by 20–40 mg q 6–8 hr until desired response. Distribution: Crosses placenta, enters breast milk. Maintenance doses may be given once or twice daily (doses up to 2.5 g/day have been used in patients with HF or renal disease). Hypertension– 40 twice daily initially (when added to regimen, ↓ dose of other antihypertensives by 50%); adjust further dosing based on response; Hypercalcemia– 120 mg/day in 1–3 doses. PO: (Children 1 mo): 2 mg/kg as a single dose; may be ↑ by 1–2 mg/kg q 6–8 hr (maximum dose = 6 mg/kg). IM: IV: (Adults) 20–40 mg, may repeat in 1–2 hr and ↑ by 20 mg every 1–2 hr until response is obtained, maintenance dose may be given q 6–12 hr; Continuous infusion– Bolus 0.1 mg/kg followed by 0.1 mg/kg/hr, double q 2 hr to a maximum of 0.4 mg/kg/hr. IM: IV: Children 1–2 mg/kg/dose q 6–12 hr; Continuous infusion– 0.05 mg/kg/hr, titrate to clinical effect. Hypertension PO: (Adults) 40 twice daily initially (when added to regimen, ↓ dose of other antihypertensives by 50%); adjust further dosing based on response. Tablets: 20 mg, 40 mg, 80 mg, 500 mg Cost: Generic: 20 mg $6.50/100, 40 mg $7.11/100, 80 mg $10.83/100Oral solution (10 mg/m L–orange flavor, 8 mg/m L–pineapple–peach flavor): 8 mg/m L, 10 mg/m LCost: Generic: 10 mg/m L $10.40/60 m LSolution for injection: 10 mg/m LLab Test Considerations: Monitor electrolytes, renal and hepatic function, serum glucose, and uric acid levels before and periodically throughout therapy. May cause ↓ serum sodium, calcium, and magnesium concentrations. May also cause ↑ BUN, serum glucose, creatinine, and uric acid levels.furosemide is a sample topic from the Davis's Drug Guide. This leaflet answers some common questions about Lasix oral medicines (tablets, oral solution) and injections. It does not take the place of talking to your doctor or pharmacist. Your doctor has weighed the risks of you taking this medicine against the benefits they expect it will have for you. Lasix contains furosemide (frusemide), which belongs to a family of drugs called diuretics. If you have any concerns about taking this medicine, ask your doctor or pharmacist. A diuretic helps reduce the amount of excess fluid in the body by increasing the amount of urine produced. Lasix is used to treat swelling of the ankles, feet, legs or even the brain or lungs. This swelling is called oedema and can occur in some heart, lung, liver or kidney conditions. Lasix may be used in some patients with more serious kidney problems who may have some fluid retention. Lasix may also be used to lower high blood pressure (which is also called hypertension). This pressure helps move your blood around your body. Your blood pressure may vary at different times of the day, depending on how busy or worried you are. Lasix 50 mg Lasix Furosemide - Side Effects, Dosage, Interactions - Drugs, DOs and DONʼTs” for Furosemide Use in Dogs VETgirl Veterinary. Prednisone walmart Rx Script Form Required Used for prompt relief of edema in horses, cattle, dogs and cats associated with cardiac insufficiency and acute noninflammatory tissue. Furosemide 50mg 100ml Inj. Vet Provisions. Furosemide Lasix Generic - Heart and Kidney Disease - PetCareRx. Lasix Oral Uses, Side Effects, Interactions, Pictures, Warnings - WebMD. For treating edema in patients with cardiac insufficiency, Lasix is prescribed at a dose of 20-50 mg per day. Depending on body reactions, Lasix dosage can be. Initially 20–50 mg, then by intramuscular injection or by intravenous injection or by intravenous infusion increased in steps of 20 mg every 2 hours if required. Furosemide answers are found in the Davis's Drug Guide powered by. by 50%; adjust further dosing based on response; Hypercalcemia– 120 mg/day in 1–3.