Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Chloroquine used whee Side effects from stopping plaquenil Plaquenil doses lupus Jul 07, 2010 In a randomized, double-blind, crossover study, seven healthy subjects with CYP450 2D6 extensive metabolizer phenotypes took 400 mg hydroxychloroquine or placebo twice daily for 8 days, and 100 mg metoprolol orally on the ninth day. Average metoprolol AUC increased by 65% and maximum plasma concentrations increased by 72%. Not all medicines respond well when taken together, and there is always the possibility of developing negative drug interactions. With metoprolol, these interactions can cause your body to metabolize the medicines differently than intended and result in problems like excessive drug levels in your system, extremely low blood pressure, slow heart rate, or low blood sugar levels, among other things. When phenothiazine medications, certain beta blockers, or certain parasite medicines are taken together with Plaquenil, interactions can occur that may affect the drug levels in your blood. This could increase your risk for side effects or decrease the effectiveness of the medicines. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Can metoprolol and plaquenil be taken together Can i take metoprolol with losartan - Answers on HealthTap, Drug Interactions With Metoprolol - Heart Disease Home Page Diflucan and plaquenil Using metoprolol can make it harder for you to tell when you have low blood sugar. Your insulin or diabetic medication needs may change while you are taking hydrochlorothiazide and metoprolol. Talk with your doctor before changing any doses. Hydrochlorothiazide and metoprolol can affect the results of certain thyroid tests. Hydrochlorothiazide and metoprolol - CardioSmart. Plaquenil Interactions - Antibiotics Home Page. Plaquenil and antacids?. I have been taking metoprol and and atenolol together for about 7 weeks now and they work great against high heart rate and blood pressure. I started the BP drugs for chronic atrial fibrilation and then became dependent on read "addicted to," if this hadn't been prescribed by a physician or PA or NP metoprolol to control BP. Just wondering if anyone out there has been put on plaquenil and enbrel together. I noticed on webmed that the 2 should not be taken together as there is a serious potential interaction. I noticed on webmed that the 2 should not be taken together as there is a serious potential interaction. Aug 16, 1999 By this method, reliable determination of the current activity of CYP2D6 can be performed. On day 9, each subject ingested 100 mg rac-metoprolol Spesicor®, Leiras, Turku, Finland with 150 ml of water at 08.00 h after a 10 h fast. A standard meal was served 4 h later.