Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Nitrofurantoin and hydroxychloroquine Bad side effects of plaquenil Is plaquenil a steroid an immunosuppressant Loss of hearing lower back or side pain noisy breathing painful or difficult urination red irritated eyes red skin lesions, often with a purple center severe mood or mental changes sore throat sores, ulcers, or white spots on the lips or in the mouth sticking out of the tongue stomach pain swelling of the feet or lower legs Visual changes and loss of vision are potential hydroxychloroquine side effects, although they most commonly occur in individuals who have taken high doses of hydroxychloroquine for long periods. Physicians will generally recommend an eye exam every six months for patients taking hydroxychloroquine long-term. Find information about common, infrequent and rare side effects of Hydroxychloroquine Oral. Hydroxychloroquine may also be used for purposes not listed in this medication guide. Hydroxychloroquine is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Does hydroxychloroquine cause vision loss Protecting your eyesight when taking Plaquenil Lupus., Hydroxychloroquine Plaquenil Success, Reviews and Side Effects Does plaquenil come in 200mg strengthHydroxychloroquine toxicity octChloroquine proguanil malaria prophylaxisChloroquine ototoxicity Vision changes/loss of vision There is a chance that retinal damage will occur while taking hydroxychloroquine Plaquenil or chloroquine Aralen. This is called known as hydroxychloroquine retinopathy. This sort of damage occurs only in 1 out of 5,000 people who take the drug for five years or more. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. Common and Rare Side Effects for Hydroxychloroquine Oral. Hydroxychloroquine Oral Uses, Side Effects, Interactions.. This means many people taking Plaquenil for RA are taking a dose of 400mg a day or higher. Pigment deposits in the retina can cause vision changes, according to Steven Ofner, M. D. of Eugene Oregon Eye Care. Signs of retinal damage include blurry or distorted vision, flashes of light or floaters, or loss of night vision. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking hydroxychloroquine and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes. Common side effects include vomiting, headache, changes in vision and muscle weakness. Severe side effects may include allergic reactions. It does not appear to be safe during pregnancy. Hydroxychloroquine is in the antimalarial and 4-aminoquinoline families of medication.