She suffered from Sjogren syndrome and inflammatory arthritis and was currently treated with prednisone and methotrexate. She was previously treated with hydroxychloroquine (Plaquenil) 200mg bid (6.5mg/kg) for 10 years, which was stopped one year prior to presentation. Aralen side effects and instructions Hydroxychloroquine liver toxicity alcohol What is hydroxychloroquine 400 mg used for Stop taking Plaquenil and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes. Before using Plaquenil, tell your doctor if you are allergic to any drugs, or if you have psoriasis, porphyria, liver disease, alcoholism, or glucose-6. A lot of things aside from Plaquenil can cause a problem within the visual fields. I developed Ra anterior uveitis while on Plaquenil but Plaquenil was not responsible. Then I developed even more visual field problems but by then, I stopped Plaquenil in favor of a combo of MTX and a biologic. Sep 13, 2019 -Patients with retinal changes may be asymptomatic initially, or may have scotomatous vision with paracentral, pericentral ring types, temporal scotomas, and abnormal color vision.-Corneal changes including edema and opacities can be symptomless or may cause disturbances such as haloes, blurring of vision or photophobia. They may be transient. Review of systems: Blurred vision, halos, dry eye, dry mouth, gastroesophageal reflux, joint pain Pupils: Reactive to light in each eye from 5 mm in the dark to 2 mm in the light. Extraocular movements: Full, both eyes (OU) Confrontation visual fields: Full OU Intra-ocular pressure The optic nerves appeared healthy with a 0.3 cup-to-disc ratio. Past Ocular History: None Medical History: Sjogren syndrome and inflammatory arthritis, supraventricular tachycardia, anxiety, depression, peptic ulcer disease Medications: prednisone, methotrexate, amitriptyline, ranitidine, estradiol, tizanidine, diltiazem, Restasis Allergies: codeine, droperidol Family History: heart disease, arthritis, cancer Social History: occasional alcohol but no tobacco or intravenous drug use. Plaquenil vision changes New Plaquenil Guidelines, Plaquenil and vision changes DailyStrength Is plaquenil safe during pregnancyHydroxy-chloroquine 200 mg without prescriptionHydroxychloroquine and corticosteroids This sort of retinal damage may result in patchy loss of central vision or patchy loss of vision just close to the centre of your vision. There are a number of other much less important side effects of Plaquenil, including changes in the cornea and changes in the eyelids. Plaquenil & Your Eyes. Plaquenil Side Effects Common, Severe, Long Term -. Rx Side Effects New Plaquenil Guidelines and More - American.. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking hydroxychloroquine and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes. Call your doctor at once if you have In rare cases, hydroxychloroquine can cause visual changes or loss of vision. Such vision problems are more likely to occur in individuals taking high doses for many years, individuals 60 years or older, or those with significant kidney disease. At the recommended dose, development of visual problems due to the medication is rare. Ocular side effects of anti-rheumatic medications what a rheumatologist should know. photophobia and central vision changes may occur. daily dosage is thought to be the most important factor in the development of hydroxychloroquine retinopathy. 110 The great majority of case reports of hydroxychloroquine toxicity occurred in individuals.