Specifically, is the risk of impaired wound healing or increased chance of infection worth avoiding the possible side effects associated with temporary cessation during the perioperative period. The appropriate use of immunosuppressants (IS) during elective surgery has been debated extensively with conflicting results, through the current body of literature. Plaquenil long term Side effects of stopping hydroxychloroquine Chloroquine retrovirus production Evidence for this comes from a randomized clinical trial in which patients with rheumatoid arthritis RA were assigned to either continue on methotrexate MTX or suspend taking it for 2 weeks before and 2 weeks after surgery. Answer. Plaquenil does not need to be stopped for surgery so it can be restarted after the procedure. Although in studies Celebrex does not cause increased bleeding, unilke other older NSAIDs, some surgeons still advise to stop it to be safe. In general, Celebrex can be restarted the day after the procedure once the risk of bleeding is over. No, never hear the need to ever stop Plaquenil before surgery. Nurse is just a Nurse.the Rhuematologist! You should be following advise straight from your Rhuematologist, not from a Nurse. I hope you have on the advise of the Rhuematogist re-commensensed back on the Plaquenil ! This discussion includes an overview of the pharmacology and use of eight of the common IS medications: azathioprine, cyclosporine, hydroxychloroquine, infliximab, leflunomide, methotrexate, methylprednisolone, and mercaptopurine. Herein, we aim to provide a comprehensive, yet streamlined, overview of the common IS medications that surgeons are likely to encounter in practice in a wide variety of patients. Stopping plaquenil before surgery How long to be off Celebrex adn Plaquenil for a Surgery., How long to be off Celebrex adn Plaquenil for a Surgery? • Johns. Deae dextran chloroquine method Three hundred and eighty-eight patients undergoing elective orthopedic surgeries were randomized to either continue or to stop MTX therapy for 2 weeks before surgery and resume 2 weeks postoperatively. The patients were followed for up to 1 year. Patients who continued their MTX had an infection rate of 2%. Perioperative Management of Medications Used in the.. Stopping Plaquenil before surgery Lupus Forums at The.. Summary of guidelines for DMARDs for elective surgery.. Nov 29, 2010 my rheumy's assistant left me a message to tell me to stop 2 weeks before my procedure, but didn't explain why. one more question for those of you who had surgery aside from going off or staying on plaquenil, did the surgery cause any noticeable flare up of your symptoms? i will certainly update you once i am back home and online again. Jan 23, 2011 No, never hear the need to ever stop Plaquenil before surgery. Nurse is just a Nurse.the Rhuematologist! You should be following advise straight from your Rhuematologist, not from a Nurse. I hope you have on the advise of the Rhuematogist re-commensensed back on the Plaquenil ! Nov 12, 2009 Plaquenil is a 6-weeker as far as the benefits are concerned, but it would be more dangerous to stop if you spend a lot of time outside and if this were the summer. If you're gonna experiment, I went off it cold turkey as it didn't hurt to do it that way, but you better get back on before the summer or you could experience a flare-up.