This study is created by e Health Me based on reports of 48,911 people who have side effects when taking Plaquenil from Food and Drug Administration (FDA), and is updated regularly. On e Health Me, you can evaluate side effects and drug interactions from 16 million FDA reports. What class of drugs is chloroquine Chloroquine dosage for malaria prevention Hydroxychloroquine and inflexizumab Plaquenil side effects on liver WebMD provides information about interactions between Citalopram Oral and qt-prolonging-agents-hydroxychloroquine. These medicines may interact and cause very harmful effects and are usually. QT prolongation is a measure of delayed ventricular repolarisation, which can cause Torsades de Pointes, ventricular tachycardia, and sudden death. A corrected QT interval QTc of greater than 500 ms or an increase in the QTc of greater than 60 ms is considered to confer a high risk of Torsades de Pointes 3. Aug 01, 2015 The patient had been treated for mild depression for nearly a year with citalopram 60 mg per day, a drug known to cause prolonged QT interval. She had also been treated with two potentially hepatotoxic drugs. Liver impairment causes selective loss of cytochrome P450 CYP 2C19 activity, the major pathway for metabolism of citalopram. You can also discuss your drugs with qualified professionals to ensure drugs are working to improve your health. The study is based on hydroxychloroquine sulfate (the active ingredients of Plaquenil) and Plaquenil (the brand name). Long qt syndrome (disorder of the heart's electrical system) has been reported by people with depression, high blood pressure, atrial fibrillation/flutter, pneumonia, schizophrenia. The results are personalized to your gender and age (0-99 ). Plaquenil and citalopram use cause qt prolongation Citalopram Disease Interactions -, Reminder Citalopram and QT Prolongation Aralen orderingAlternatives to plaquenil for lupusIs chloroquine an anitbioticChloroquine malaria resistance Identify risk factors for QT prolongation TABLE 1. 2. When multiple risk factors are present, strive to use drugs with less potential to cause QT prolongation TABLE 2. 3. If a drug with higher potential TABLE 3 is necessary and an alternative cannot be used, monitoring is recommended. QTc Prolongation With Antidepressants and Antipsychotics. Citalopram-Induced Long QT Syndrome and the Mammalian Dive Reflex. What Drugs Cause QT Prolongation?. Citalopram is a selective serotonin reuptake inhibitor with a favorable cardiac-safety profile. Corrected QT interval QTc prolongation and cardiac arrhythmias have not been previously reported in association with citalopram use except in the presence of overdose, abnormal electrolyte values, or renal or liver failure. Heart rhythm changes warning Citalopram use can cause heart rhythm changes called QT prolongation or Torsade de Pointes, which can cause sudden death. Warning against taking with MAOIs Unless. We present a case of a syncopal episode resulting from significant QT interval prolongation in a patient on hydroxychloroquine for the treatment of systemic lupus erythematosus and end stage renal disease. The patient had been treated with hydroxychloroquine for two years prior to presentation. After thorough workup for secondary causes of QT interval prolongation hydroxychloroquine was.