Is chloroquine a quinolone

Discussion in 'Cheap And Quality Drugs' started by minime, 07-Mar-2020.

  1. Graff User

    Is chloroquine a quinolone


    It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc.

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    Chloroquine is the generic form of the brand-name prescription medicine Aralen, which is used to prevent and treat malaria — a mosquito-borne disease caused by a parasite — and to treat amebiasis, an infection of the intestines caused by a parasite. Quinine. Quinine was first extracted from the bark of the South American cinchona tree and isolated. In 1944, the total synthesis of quinine was achieved by Woodward and Doering. 124 Quinine exhibits specific toxicity against Plasmodium and has antipyretic fever-reducing activity. Oct 01, 2018 Chemically, it is 7-chloro-4- 4- diethylamino-1-methylbutylaminoquinoline phosphate 12 andhas the following structural formula C 18 H 26 ClN 3.2H 3 PO 4 Molecular Weight 515.87 Each tablet contains 500 mg of Chloroquine phosphate USP, equivalent to 300 mg Chloroquine base.

    The most serious adverse effects affect the eye, with dose-related retinopathy as a concern even after hydroxychloroquine use is discontinued. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea.

    Is chloroquine a quinolone

    Fluoroquinolone Antibiotics Linked to Serious Nerve Damage, Quinine - an overview ScienceDirect Topics

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  6. Chloroquine is an anti-malaria medicine that works by interfering with the growth of parasites in the red blood cells of the human body. Parasites that cause malaria typically enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia.

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    Chloroquine and hydroxychloroquine belong to the quinolone family. Although their therapeutic and toxic doses differ, they are related drugs with similar clinical indications for use and similar manifestations of retinal toxicity. Initially, chloroquine was given for malaria prophylaxis and treatment. One older anti-malarial drug, Chloroquine, was discovered in 1934 at Bayer laboratories. In fact the origins of the quinolone class are from the use of chloroquine as an antimalarial. A compound isolated from the commercial preparation of chloroquine was modified to produce the first marketed quinolone, nalidixic acid. Quinolones have few adverse effects, most notably nausea, headache, dizziness, and confusion. Less common but more serious adverse events include prolongation of the corrected QT interval.

     
  7. Ray Well-Known Member

    Quinine comes from the bark of a tree native to South America. Antimalarial drugs An overview - UpToDate Antimalarial Drugs and Drug Resistance Saving Lives. Malaria Consortium - Drug Resistance Pages
     
  8. Elff Moderator

    Plaquenil (hydroxychloroquine) belongs to a group of medicines called quinolines. Chloroquine - FDA prescribing information, side effects and uses Hydroxychloroquine Plaquenil Hydroxychloroquine Side Effects, Dosage, Uses, and More
     
  9. ZanderXML Well-Known Member

    Plaquenil Hydroxychloroquine - Side Effects, Dosage. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as.

    Common and Rare Side Effects for Plaquenil Oral
     
  10. surpris Moderator

    Will you have Alcohol interaction with Plaquenil - eHealthMe Alcohol interaction is found among people who take Plaquenil, especially for people who are female, 40-49 old, also take medication Elavil,

    Plaquenil and drinking - Sjogren's World