Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Dermatomyositis rash and plaquenil Benefits of plaquenil for rheumatoid arthritis Antimalarial drugs chloroquine and primaquine Answer Plaquenil, or hydroxychloroquine HCQ, is an anti-malarial medication that has been proven to be useful in the treatment of patients with rheumatoid arthritis RA, sys- temic lupus erythematosus SLE and other inflammatory and autoimmune diseases. In Sjögren’s syndrome, HCQ is believed to improve oral and ocular eye signs and symp- toms and has been shown to reduce inflammatory markers in saliva and serum, such as sedimentation rates and C-reactive protein levels. As part of the inflammatory response, your body increases its production of white blood cells, immune cells, and substances called cytokines that help fight infection. Classic signs of acute short-term inflammation include redness, pain, heat, and swelling. Low-dose naltrexone LDN has been demonstrated to reduce symptom severity in conditions such as fibromyalgia, Crohn’s disease, multiple sclerosis, and complex regional pain syndrome. We review the evidence that LDN may operate as a novel anti-inflammatory agent in the central nervous system, via action on microglial cells. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Plaquenil help decrease inflammation Plaquenil Hydroxychloroquine MyPsoriasisTeam, Anti-Inflammatory Diet 101 How to Reduce Inflammation. Plaquenil guidelines 2018Is chloroquine in liquidPlaquenil c 24-2 Another alternative is a more targeted approach. I don't know a lot about Sjogrens but there are medicines like Restasis to help with dry eyes. They suppress the inflammation in just the eyes rather than suppressing the immune system for the entire body. There are also drugs to increase the production of saliva in the mouth. Do either hydroxychol/Plaquenil put you at risk for greater.. The use of low-dose naltrexone LDN as a novel anti.. Hydroxychloroquine Plaquenil. Plaquenil lowers your immune system’s ability to cause inflammation. This can help control symptoms like rashes, skin and mouth sores and joint pain. Plaquenil and your eyes A rare side effect of Plaquenil is damage to the eye's retina. The retina is the light-sensitive tissue at the back of the eye. But Plaquenil, in it's original form is probably the first "drug discovered by man. As a tree bark, it was chewed to help with the symptoms of malaria and even to prevent malariaand it's still used for both. These medications help reduce pain, but have no effect on inflammation. An over-the-counter option includes acetaminophen Tylenol, others. For more-severe pain, opioids might be prescribed, such as tramadol Ultram, ConZip, oxycodone OxyContin, Roxicodone, others or hydrocodone Hysingla, Zohydro ER.