This study is created by e Health Me based on reports of 48,911 people who have side effects when taking Plaquenil from Food and Drug Administration (FDA), and is updated regularly. On e Health Me, you can evaluate side effects and drug interactions from 16 million FDA reports. Plaquenil chronic urticaria Chloroquine phosphate and prime Hydroxychloroquine when to take People with polymorphous light eruption or photosensitivity caused by systemic lupus erythematosus lupus may benefit from topical corticosteroids or oral hydroxychloroquine or corticosteroids. Occasionally, people with polymorphous light eruption can be desensitized to the effects of sunlight by gradually increasing their exposure to UV light see Phototherapy Using Ultraviolet Light to Treat Skin Disorders. A side effect of some RA medicine is sun sensitivity. Be extra careful to avoid skin burns, blistering, and the infections that may result. If you have lupus, you might be photosensitive -- meaning you have an unusually strong reaction to sunlight. In fact, about two-thirds of the people with lupus are UV light-sensitive. Many experience an increase in lupus symptoms after being exposed to ultraviolet UV rays, either from the sun or from artificial light. You can also discuss your drugs with qualified professionals to ensure drugs are working to improve your health. The study is based on hydroxychloroquine sulfate (the active ingredients of Plaquenil) and Plaquenil (the brand name). Photosensitivity reaction has been reported by people with rheumatoid arthritis, high blood pressure, depression, idiopathic pulmonary fibrosis, multiple sclerosis. The results are personalized to your gender and age (0-99 ). Hydroxychloroquine and sun sensitivity Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria, Rheumatoid Arthritis Medication Beware of Sunburn if You. Hydroxychloroquine vs chloroquine Photosensitivity, also called sun sensitivity, is an inflammation of the skin caused by a combination of certain chemicals and exposure to the sunlight. 1 Some medications commonly taken for RA may contain these light-activated chemicals. Exposure to either the light or the chemical alone is not enough to cause the reaction. Photosensitivity A Side Effect of RA Medications. Lupus Photosensitivity and UV Light. Plaqunil rash -. Jun 22, 2010 Skin rashes occasionally develop and hydroxychloroquine may make you more sensitive to the sun, so it is advisable to use the usual precautions of sunscreens and a hat if you are in the sun. Also, your hair may become a little bleached with the drug and rarely a degree of thinning of the hair can develop. Lupus patients have to stay out of the sun -the sensitivity and my rashes, lupus body flares increased drastically if I am in the sun. We are instructed to wear sunscreen underneath our clothing – you can use RIT -Sun Guard to wash your clothes and it gives it a 30 SPF for about 20 washes. It usually occurs after the first dose of a drug and within 24 hours of taking the drug and exposure to the sun. Symptoms include severe redness on the areas of skin exposed to light, akin to an exaggerated sunburn with severe tenderness.