I did stop it for 2 weeks early in the treatment due to having to take a coupld other drugs that seemed to give me side effects. I just quit the plaquenil to give my liver a rest at that time. Plaquenil isn a antiparasitic drug with anti-inflammatory affect. Treatment of cerebral malaria chloroquine Plaquenil side effects blood pressure Icd 10 plaquenil therapy Hydroxychloroquine pregnancy category Plaquenil isn a antiparasitic drug with anti-inflammatory affect. I have done a lot of research on this drug and haven't run into anybody who has complained of the withdrawal effect. Over the years on this site we have had quite a few people post that they didn't think that the plaquenil was working so they would stop taking it. Nov 17, 2011 If you have a tolerance for methadone and just suddenly stop taking it, you will begin to experience withdrawals such as nausea, body aches, hot and cold sweats, and diarrhea. You should slowly taper off of methadone instead of quitting cold turkey. Jul 24, 2010 Unfortunately, it's not a good idea to stop methotrexate "cold turkey.". Some people experience no side effects to suddenly stopping taking this medication, but it does have the potential for creating an intense RA flare. The goal of medication is to protect your joints and other systems in the body internal organs, such as the heart. Over the years on this site we have had quite a few people post that they didn't think that the plaquenil was working so they would stop taking it. I have done a lot of research on this drug and haven't run into anybody who has complained of the withdrawal effect. Stopping plaquenil suddenly Hydroxychloroquine Oral Route Proper Use - Mayo Clinic, What will happen if you stop taking plaquenil - Answers Chloroquin site drugs.com Plaquenil-induced toxicity usually will not occur before five years of taking the drug. “Eye damage due to Plaquenil is not common,” he says. “Rarely will anybody who has good vision and minimal symptoms develop loss of central vision or ability to read if annual screening is done and visual are symptoms reported as soon as they occur so the medication can be stopped if toxicity occurs. Protecting your eyesight when taking Plaquenil Lupus.. What Are The Side Effects Of Stopping Methotrexate?. Stopping Methotrexate - Arthritis Information. Hello all, I am currently new to this site and ran across the discussion about stopping Plaquenil. I have been taking Plaquenil for about 8-9 months and thought that it was not helping me because I still have a fair amount of joint pain, fatigue, muscle pain and so many other issues. I recently decided to stop taking Plaquenil because I was having constant chest pains even more so than I usually have due to Lupus. Since I have not taken it my chest feels so much better which is odd because chest pain is not listed as a side effect. Also I noticed that the Plaquenil I think was making me feel different but not in a good way. SSRI Discontinuation Citalopram is an ssri antidepressant. If you stop it or any of its relatives suddenly, you may experience discontinuation withdrawal symptoms. These can be uncomfortable, and include dizziness, nausea, sweating, tremor, confusion, vertigo, and electric "zap" type sensations.