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    Sometimes premature ejaculation (PE) is a problem in men who also have Erectile Dysfunction (ED). ED is the inability to achieve or maintain an erection that is firm enough for satisfactory sexual intercourse. PE is where a man ejaculates too quickly after the initiation of sexual intercourse. The definition of ‘too quickly’ is not set in stone, it depends very much on the individual and what the man and his partner deem satisfactory. PE may be caused by ED, especially in a man who needs continued penile stimulation to maintain his erection. Both medications cause the effect of lowering of blood pressure. Viagra is a safe treatment for ED, and Priligy is a treatment for PE. Together, the combined effect may be to reduce blood pressure to a low enough level that symptoms such as fainting will occur (known as orthostatic hypotension). This occurs when there is a drop in blood pressure when the person stands up and causes dizziness, lightheadedness and possible fainting. As a member of the selective serotonin reuptake inhibitor (SSRI) family, dapoxetine was initially created as an antidepressant. However, unlike other SSRIs, dapoxetine is absorbed and eliminated rapidly in the body. Its fast acting property makes it suitable for the treatment of PE but not as an antidepressant. Originally created by Eli Lilly pharmaceutical company, dapoxetine was sold to Johnson & Johnson in 2003 and submitted as a New Drug Application to the Food and Drug Administration (FDA) for the treatment of PE in 2004. Different dosage has different impacts on different types of PE. Dapoxetine 60 mg significantly improves the mean intravaginal ejaculation latency time (IELT) compared to that of dapoxetine 30 mg in men with lifelong PE, but there is no difference in men with acquired PE. Dapoxetine, given 1–3 hours before sexual episode, prolongs IELT and increases the sense of control and sexual satisfaction in men of 18 to 64 years of age with PE.

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