Implementation of the guideline’s recommendations will prevent iatrogenic visual loss. The new guideline also makes recommendations regarding the techniques and timing of baseline and follow-up screening tests for both hydroxychloroquine and chloroquine retinopathy. Chloroquine kills sporozoites Plaquenil cause menstrual cycle Chloroquine intercalation The 2016 guidelines recommend the following. Screening intervals. All patients who are placed on long-term HCQ treatment should have a baseline screening within the first year of beginning treatment. An initial fundus evaluation of the macula is critical to rule out preexisting disease that might make the retina more susceptible or. Ocular Surgery News The American Academy of Ophthalmology has published several dosing and screening recommendations for hydroxychloroquine to avoid potential retinal toxicity, yet some patients. Screening for chloroquine and hydroxychloroquine retinopathy. Ophthalmology. 92 2011;1182415-22. 93 5. Marmor MF, Kellner U, Lai TY, Melles RB, Mieler WF, American Academy of O. 94 Recommendations on Screening for Chloroquine and Hydroxychloroquine Retinopathy 2016 95 Revision. Ophthalmology. 2016. 96 6. In general, hydroxychloroquine is a safe and cost-effective medication, particularly when compared to newer anti-inflammatory medicines which can more significant adverse effects on the body. Hydroxychloroquine is a medicine that is effective in treating various long-term inflammatory disorders of the joints and skin. New guidelines for plaquenil screening Hydroxychloroquine And Chloroquine Screening 2016 AAO., Despite Plaquenil dosing recommendations, retinal toxicity remains Hydroxychloroquine suppress immune systemWhat does chloroquine do in gelProzac and plaquenil New Plaquenil Guidelines Here is a look at the 2011 testing guidelines for patients on Plaquenil guidelines. Diana L. Shechtman, O. D. and Paul M. Karpecki, O. D. AAO established ocular examination guidelines for screening patients on Plaquenil therapy. New Plaquenil Guidelines -. AMERICAN COLLEGE OF RHEUMATOLOGY. Recommendations on Screening for Chloroquine and Hydroxychloroquine.. In 2011 the American Academy of Ophthalmology published new clinical guidelines for appropriate annual screenings for those patients taking Plaquenil. These guidelines are much different from the previous 2002 recommendations, and many practicing doctors were trained with the 2002 guidelines in mind. Newer guidelines state that daily dose 5mg/kg of real weight/day can lead to toxicity. Retinal toxicity is irreversible and can progress after cessation of hydroxychloroquine, thus early screening is important to limit potential vision loss. Baseline screening and annual screening after five years is recommended. Rheumatoid Arthritis. The action of hydroxychloroquine is cumulative and may require weeks to months to achieve the maximum therapeutic effect see CLINICAL PHARMACOLOGY. Initial adult dosage 400 mg to 600 mg 310 to 465 mg base daily, administered as a single daily dose or in two divided doses. In a small percentage of patients, side effects may require temporary reduction of the initial.