I can't say that the drug has helped at all, but it is difficult to compare todays pain with that of 6 months ago. Still get mysterious rashes, fevers and other odd symptoms. Asked my primary to check my thyroid after taking a bovine herbal thyroid med for 2 weeks. Then they worked out it was my liver causing my liver and that I could go back on Plaquenil. I have gained nearly 25 lbs now and I can' t stand it, but when I try an dexercise it is as if my muscles just will not relax, the are tight and it hurts to even do the lightest yogo! I took 60mg for a year and only 30 this past month. NOw if my thyroid isn't working I've hidden it from my dr... Well, within 3 days my non-liver symptoms were way better. Chloroquine and brain cancer How longbto take plaquenil after alcohol Replacement for hydroxychloroquine Plaquenil hydroxychloroquine ocd Aug 29, 2014 One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Hi, although Plaquenil is prescribed for autoimmune diseases, such as yours, it can actually add to/increase the number of the symptoms. Muscle damage and leg pain being just 2 examples. It is great that you have responded so well to the new medication. I saw a rheumatologist who said "no the nausea is at the start before you get use to it etc, but just come off it for 2 weeks to 'prove this doctor wrong'". Don't know what I was thinking but my thyroid showed 1.59 (0,47-4.68)... Since then I've had one flare up of my hips and finger joints, which lasted for about 2-3 days (typically my flares last a few weeks). I'd say they're 90-95% better than this time last year. Plaquenil cause muscle pain Plaquenil Hydroxychloroquine - Side Effects, Dosage., Plaquenil Oral Uses, Side Effects, Interactions. Chloroquine interactionsChloroquine phosphate degradationCost hydroxychloroquine Talk to your doctor about this, but my guess is that the Plaquenil is not doing anything to cause the pain, but rather that it is not doing enough to prevent it. It sounds like your RA has probably gotten a bit out of control, relative, to your current treatment, and Plaquenil is not a particularly potent drug when it comes to managing joint pain. Plaquenil and pain" Rheumatoid Arthritis Community.. Hydroxychloroquine - thigh muscle weakness?. Hydroxychloroquine Plaquenil. Plaquenil and Joint pain - from FDA reports Summary Joint pain is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years, also take medication Enbrel, and have Pain. Sep 24, 2010 I went in to my Rheum this week because I was having a lot more pain, burning, and muscle fatigue, particularly in my legs and arms, especially at night while I'm trying to sleep. He told me to stop the Plaquenil because sometimes it can cause nerve damage. He told me to stop it for two weeks and come back in. He said nerve damage is a side effect. I agree with CameronC and all others who are "pro" Plaquenil. I was diagnosed with Limited Systemic Scleroderma in late 2001 & started Plaquenil at the beginning of 2002. Joint and muscle pain and overwhelming fatigue were my worst symptoms.