We aimed to compare the efficacy and safety of HCQ and corticosteroid treatment in patients with Ig AN. Ninety-two patients with Ig AN who received HCQ in addition to routine renin-angiotensin-aldosterone system inhibitors (RAASi) therapy were included. Ninety-two matched historical controls who received corticosteroids were selected by propensity score matching. Baseline proteinuria levels were comparable between the HCQ and corticosteroid groups (1.7 [1.2, 2.3] vs. The percentage reduction in proteinuria at 6 months was smaller in the HCQ group than in the corticosteroid group (− 48.5% [− 62.6, − 31.4] vs. The time averaged proteinuria within the 6 months of observation was comparable for the HCQ and corticosteroid groups (1.1 [0.8, 1.5] vs. The cumulative frequency of patients with a 50% reduction in proteinuria during the study was also comparable between the two groups (52.2% vs. However, six of the 92 (6.5%) patients suffered from severe adverse events (SAEs) in the corticosteroid group, while no SAEs were observed in the HCQ group (6.5% vs. The antiproteinuric effect of HCQ might be slightly inferior to that of corticosteroids over 6 months in patients with Ig AN who were deemed to be candidates for HCQ and not corticosteroids treatment. Hydroxychloroquine risks Plaquenil side effects go away Chloroquine blood bank Yes, if the plaquenil controls your Lupus flares, it is best to not use the prednisone. I hope you can get off of it completely, or at least take a small maintenance dose. Take it very slow, tapering off, and if you have a reaction, severe fatigue, etc, talk to your doc, about tapering down even slower. Rheumatoid arthritis RA, the most common form of inflammatory arthritis, can lead to significant pain, disability, and deformity, and is a multisystem autoimmune disorder. steroid therapy has been shown to increase infection rates and impede wound healing. Plaquenil™, leflunomide Arava™, azathiaprine Imuran™, or. Yes, anti-malarials can be taken with other lupus medications, including corticosteroids e.g. prednisone, immunosuppressives, cytotoxic drugs, and NSAIDs. Anti-malarial drugs may be given in combination with prednisone to reduce the amount of steroid needed to control lupus symptoms and thus to alleviate some of the side effects of the steroid. Ig A nephropathy (Ig AN) is the most prevalent type of primary glomerulonephritis worldwide . However, HCQ treatment was safer than corticosteroid treatment. Corticosteroids vs plaquenil Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus, Perioperative Management of Medications Used in the. Hydroxychloroquine can it shrink spleenCan i take my celebrex and plaquenil doses togetherLupus miliaris disseminatus faciei hydroxychloroquine Lbs or less - up to 200 mg Plaquenil daily; A lupus patient explains her changes in vision. Ann Utterback, 67, a broadcast voice specialist who lives in Gaithersburg, Md. was diagnosed with lupus in 2005. She says she’s always been extra-sensitive to medications, and her vision loss is related to both corticosteroids and Plaquenil. Protecting your eyesight when taking Plaquenil Lupus.. Treating Lupus with Anti-Malarial Drugs Johns Hopkins.. Prednisone/Plaquenil question -. Corticosteroids remain the initial drug of choice for treat- ment of parenchymal lung diseases. A starting dosage is 20 - 40 mg prednisone or its equivalent. Once corticosteroids have been started, the patient is usually seen 1-3 months. Depending on the patient's condition, the dosage can be tapered at those visits. Plaquenil is an arthritis medication and an anti infectious agent. Prednisone is a steroid. There may be a negative interaction between Plaquenil and alcohol. There may be a negative interaction between Prednisone and alcohol. Apr 09, 2008 This guide summarizes evidence comparing the effectiveness and safety of disease-modifying antirheumatic drugs DMARDs and corticosteroids used for rheumatoid arthritis RA. It does not address other drugs that are no longer commonly used as first-line treatment for RA, such as azathioprine, chloroquine, cyclosporine, gold, and penicillamine.