It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Can plaquenil lower antibodies to thyroid Can you take robitussin and hydroxychloroquine together Hydroxychloroquine ranbaxy The patient complained of progressive proximal upper and lower extremity painless muscle weakness since being discharged from the hospital for a bladder suspension surgery 4 weeks before. Her hospitalization was complicated by a postoperative gout flare of multiple metatarsophalangeals on the right. I've been taking Plaquenil 400 mg for nearly 6 mos. I didn't seem to have any problems whatsoever with it initially, other than very short term and mild cramping/diarrhea. But now I've been dealing with considerable muscle aching and pain/spasm in some new places - or at least places that haven't bothered me in quite awhile. Combining telbivudine Tyzeka and hydroxychloroquine may increase the risk of unexplained muscle pain, tenderness, or weakness because both drugs cause such side effects. Hydroxychloroquine suppresses the immune system and should not be combined with drugs that also suppress the immune system or live vaccines. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Forgot plaquenil muscle weakness Ask the Expert Plaquenil and Sjögren’s, Plaquenil and muscle aches and pains? - Plaquenil antimalarial drug Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. Plaquenil and muscle aches and pains?. Side effects of Plaquenil and Aralen that are similar include nausea, vomiting, stomach pain or cramps, diarrhea, headache, or hair loss. Side effects of Plaquenil that are different from Aralen include loss of appetite, weight loss, dizziness, spinning sensation, ringing in your ears, mood changes, nervousness, irritability, skin rash, or itching. Muscle weakness out of the blue is definitely worth mentioning to your doctor. It could be overexertion or something else that needs looking into. That said, I have a lot of weakness in my legs as well. It gets worse when I overdo myself. Heck, I have overall weakness when I overdo myself. Hopefully if you rest as much as you can it'll get better. At the time, she started treatment with Mestinon pyridostigmine and underwent surgical removal of the thymus, or thymectomy, which significantly improved her muscle weakness. About 23 years later, she was diagnosed with lupus and started treatment with Plaquenil hydroxychloroquine to manage joint swelling and tenderness.