In Sjögren’s, Plaquenil is used to treat many symptoms of Sjögren’s including fatigue, joint symptoms of arthritis and arthralgias (joint pain), dry mouth and dry eyes. Similar to its use in systemic lupus erythematosus, many clinicians feel that it is useful in reducing general Sjögren’s “disease activity.” One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. Plaquenil dosage sjogren's syndrome Plaquenil and hearing loss Plaquenil dose for sle Hydroxychloroquine serious side effects Plaquenil and Acute kidney failure - from FDA reports Summary Acute kidney failure is found among people who take Plaquenil, especially for people who are female, 50-59 old, have been taking the drug for 1 - 2 years, also take medication Enbrel, and have Osteoporosis. Although they are uncommon, Plaquenil has side effects that may affect your eyes. Plaquenil and Your Eyes In some people, Plaquenil can cause a condition called hydroxychloroquine retinopathy, often referred to as bulls-eye maculopathy. Jan 05, 2020 Hydroxychloroquine Plaquenil and chloroquine cause ocular toxicity to various parts of the eye such as the cornea, ciliary body, and retina. Chloroquine can also induce cataract formation; however, no reports of hydroxychloroquine and cataract have been reported 1. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. Is plaquenil harmful Hydroxychloroquine Plaquenil, Plaquenil Side Effects on Your Eyes and Vision Plaquenil black box warningHow to quit taking hydroxychloroquineInj chloroquine dose Aug 14, 2017 Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. The New Zealand Dermatological Society recommends that to decrease the risk of retina damage, no more than 200mg of Plaquenil should be taken a day, and a dose of 400mg per day should be taken no longer than a few weeks. Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis.. Hydroxychloroquine toxicity - EyeWiki. Bad Side Effects of Plaquenil -. Plaquenil is in a class of medicines known as antimalarials. It's a less toxic version of the older antimalarials, including quinine and chloroquine. The drug is also in a group of biologic medicines known as disease-modifying anti-rheumatic drugs DMARDs, because of its effects on autoimmune illnesses. Plaquenil is generally well-tolerated, but side effects are possible. Common side effects linked to Plaquenil include nausea and diarrhea. Taking the medication with food eases nausea for most people taking the drug. Less common side effects include skin rashes, hair thinning, and weakness. Plaquenil has replaced chloroquine because it produces less retinal side effects. Aside from its initial intended use, it has been also used for the management of rheumatoid arthritis, systemic lupus erythematosus and several other connective tissue disorders 1. Although it is considered rare.