Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Plaquenil 100mg tablet doses Half life of hydroxychloroquine sulfate The weight and appetite loss actually started some time before starting the plaquenil though! level 1. 3 points 7 months ago. Plaquenil can cause loss of appetite and weight loss. level 2. 1 point 7 months ago. The loss of appetite and weight loss started a month before I started the plaquenil. Appetite decreased is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months, also take medication Enbrel, and have Pain. In 1956, the U. S. Food and Drug Administration approved HCQ for symptoms of lupus and rheumatoid arthritis, particularly skin inflammation, hair loss, mouth sores, fatigue, and joint pain. Dosing. Hydroxychloroquine is generally prescribed at a daily dose of 6.5 milligrams or less per kilogram of body weight. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil loss of appetite Nausea and loss of appetite - Blog - Sjogren's Syndrome Support, Will you have Appetite decreased with Plaquenil - eHealthMe Chloroquine irelandHow soon does hydroxychloroquine work Plaquenil is a prescription medication used to reduce pain and swelling caused by diseases of the immune system such as rheumatoid arthritis, juvenile arthritis, and systemic lupus erythematosus SLE. This medication belongs to a group of drugs called DMARDs disease modifying antirheumatic drugs which work by suppressing the excessive activity of the immune system. Plaquenil - Side Effects, Uses, Dosage, Overdose.. Drug spotlight on hydroxychloroquine Lupus Foundation of.. Plaquenil Side Effects - Antibiotics Home Page. I've been on plaquenil for a few years and unfortunately I have never noticed any loss of appetite from it. Unfortunately I was also on prednisone when I began this. Also, unfortunately I have been on several med school and even have celiac that warns of a potential of excessive weight loss. Apr 10, 2019 Plaquenil side effects. Get emergency medical help if you have signs of an allergic reaction to Plaquenil hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye. Yes, Plaquenil causes both weight loss and loss of appetite. Hence, if the loss of appetite and weight loss started after you started on this drug, then yes, it could be due to Plaquenil. However, if you had loss of appetite and weight loss before your started this drug, then the drug can aggravate the process.