Chloroquine is now uncommonly used in favor of its derivative hydroxychloroquine. In the United States, hydroxychloroquine is most often used for its anti-inflammatory effects in rheumatology and dermatology. Interaction hydroxychloroquine sulfate & wellbutrin Hydroxychloroquine and caffeine The American Academy of Ophthalmology released an updated set of screening recommendations for hydroxychloroquine Plaquenil and chloroquine to account for the many studies that have shown the effects of these medications on the retina 1. It succinctly makes the case for screening, and The Royal College of Ophthalmologists RCOpth published guidance on hydroxychloroquine and chloroquine retinopathy screening in 2018. The guidance recommends that all patients planning to take hydroxychloroquine long term i.e. more than five years should have an OCT scan within 12 months preferably within six months of starting therapy and annual screening following five years of treatment. Chloroquine retinopathy, is a form of toxic retinopathy damage of the retina caused by the drugs chloroquine or hydroxychloroquine, which are sometimes used in the treatment of autoimmune disorders such as rheumatoid arthritis and systemic lupus erythematosus. This eye toxicity limits long-term use of the drugs. While early toxicity may be asymtomatic, patients with more advanced stage of toxicity may complain of color vision changes or paracentral scotomas. Its toxic effects on the retina are seen in the macula. Chloroquine retinopathy screening Hydroxychloroquine retinopathy A review of imaging, Statement hydroxychloroquine and chloroquine retinopathy. Eye doctor hydroxychloroquinePlaquenil urticaria schnitzler syndromeSanofi plaquenilHydroxychloroquine eye exam frequencyStopping plaquenil suddenly The recommendations on eye screening for hydroxychloroquine or chloroquine retinopathy have been revised by the American Academy of Ophthalmology. 22 It is strongly recommended that all patients beginning hydroxychloroquine or chloroquine therapy have a baseline examination within the first year of starting the drug to document any complicating. Chloroquine Retinopathy - an overview ScienceDirect Topics. Chloroquine retinopathy - Wikipedia. Hydroxychloroquine Plaquenil Toxicity and.. Screening Guidelines In 2002, the AAO published its initial Preferred Practice Patterns for HCQ retinopathy screening in response to the diverse regimens being advocated at the time. 9 These recommendations were revised in 2011 to reflect the increased sensitivity of newer diagnostic imaging techniques. 4 Chloroquine is a potent drug used for the treatment of various diseases, including malaria and a range of connective tissue disorders. Chloroquine retinopathy is an important complication that may appear even years after cessation of the drug, presenting with impaired visual acuity, central vision loss and progressive damage that could result in irreversible blindness. A detailed patient. Even when the clinician and patient adhere to screening guidelines and retinopathy is detected in a sub-clinical stage, discontinuation of chloroquine or hydroxychloroquine therapy may not stop the progression of retinopathy to a stage where the patient loses vision.