In some cases, they may not be available in all strengths or forms as the brand-name drug. Sulfasalazine is used to reduce inflammation and pain in rheumatoid arthritis (RA), juvenile rheumatoid arthritis (JRA), and ulcerative colitis (UC). Plaquenil 300 mg How to tell if plaquenil is working Chloroquine cutaneous lupus Methotrexate Sulphasalazine Hydroxychloroquine ABSOLUTE CONTRAINDICATION. or sulfasalazine. with patients commonly taking two or I started taking sulfasalazine SZS with Plaquenil 2 months ago for RA. Immediately felt dizzy, confused, nosebleed and depression and also severe vision changes. Bi-Weekly blood draws were a total painful waste of time. Then began a very intense ringing in my ears. Discontinued Plaquenil twice a day, and dropped the SZS from 4 per day to 3. Hi, I was diagnosed with RA and was put on sulfa, my rheumy tried adding mtx but i had awful side effects so am now on hydroxychloroquine and sulfa.this combination worked for anyone? just wondered how other people got on with it. It’s used to decrease pain and swelling in the joints. In RA and JRA, the medication is used to treat people who haven’t responded to other therapies. Sulfasalazine taken with hydroxychloroquine Sulfasalazine User Reviews for Rheumatoid Arthritis at., Sulfasalazine User Reviews for Rheumatoid Arthritis at Chloroquine phosphate side effects on fish Summary Drug interactions are reported among people who take Sulfasalazine and Plaquenil together. This study is created by eHealthMe based on reports of 7,132 people who take Sulfasalazine and Plaquenil from Food and Drug Administration FDA, and is updated regularly. Sulfasalazine and Plaquenil drug interactions - eHealthMe. Combination hydroxychloroquine and sulfasalazine - do.. Hydroxychloroquine sulfate and Sulfasalazine drug interactions - eHealthMe. Sulfasalazine is a disease-modifying anti-rheumatic drug DMARD indicated for the treatment of adults and children over 6 with RA who have not responded to non-steroidal anti-inflammatory drugs NSAIDs. DMARDS decrease the pain and swelling of inflammatory arthritis and may also prevent damage to. O'Dell J R, Leff R, Paulsen G, Haire C, Mallek J, Eckhoff P J. et al Treatment of rheumatoid arthritis with methotrexate and hydroxychloroquine, methotrexate and sulfasalazine or a combination of the three medications results of a two year, randomized, double‐blind, placebo‐controlled trial. Arthritis Rheum 2002 46 1164–1170.1170 Take sulfasalazine after a meal or with a light snack, then drink a full glass of water. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take sulfasalazine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.