Her rheumatologist instructed her to undergo a baseline ocular examination prior to initiating Plaquenil (hydroxychloroquine, Sanofi-Aventis) therapy. Toxic maculopathy associated with chloroquine use was first documented in the literature five decades ago.1 In the United States, Plaquenil––an analog to chloroquine––is used to treat a variety of conditions, including rheumatoid arthritis, lupus and several distinct inflammatory disorders. Although the incidence of macular toxicity is infrequent with Plaquenil use (at a dosage of 200mg or 400mg q.d.), its visual impact can be devastating. How is hydroxychloroquine taken Humira and plaquenil If you’re short, the standard prescription of 200 mg of Plaquenil, twice daily, is too much, he said. The recommended dosage is no more than 6.5 mg/kg/day, using the standard known as “ideal weight,” which factors in height. Adult dosing ranges from 200 mg or 400 mg per day 6.5mg/kg. In some cases, higher doses can be used. It is recommended one tablet twice daily if taking more than one tablet. It is recommended to be taken with food. Do I need a prescription for hydroxychloroquine Plaquenil? What are the side effects of hydroxychloroquine Plaquenil? What is the dosage for hydroxychloroquine Plaquenil? Which drugs or supplements interact with hydroxychloroquine Plaquenil? Is hydroxychloroquine Plaquenil safe to take if I'm pregnant or breastfeeding? Initially, central visual acuity may be unaffected, but the patient may notice related paracentral scotomas that often interfere with reading. The associated classic retinal toxicity is described as a bull’s eye maculopathy (ring of depigmented retinal pigment epithelium that spares the foveal area). How often do you take plaquenil Hydroxychloroquine Side Effects, Dosage, Uses, and More, Hydroxychloroquine Plaquenil H-chloroquine side effectsPlaquenil long termHydroxychloroquine ingredientsHow much does hydroxychloroquine cost High-risk patients would include those who have taken high doses of Plaquenil for years i.e. 1000 g. for over 7 years. are 60 years or older. are obese. have significant liver or kidney disease. have pre-existing retinal, macular disease, or cataracts. Taking Plaquenil for Rheumatoid Arthritis. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. Hydroxychloroquine MedlinePlus Drug Information. Recent findings suggest that Plaquenil toxicity can develop among patients that are taking the drug at a daily dose lower than the suggested “safe” dose and/or have been on Plaquenil for shorter than five years. My question is for those that have taken Plaquenil/Hydroxychloroquine. How long did it take for it to remove symptoms in your personal experience? I know I've read it can take up to 6 months but what I'm wondering is, do you just wake up one day and find it's kicked in 6 months down the road or more likely, it starts to work slowly over 6 months? Retinal damage. Plaquenil may cause irreversible damage to the retina the back of the eye where vision is created. You are required to have an eye exam before taking Plaquenil, then a follow-up as often as needed while taking Plaquenil. Tell your healthcare provider right away if you have some or all of the following symptoms.